Restylane® and Perlane®
Smoothing out folds and wrinkles by adding volume can make an enormous difference to your appearance. Restylane is made in Sweden, a nation known for health, nature, beauty and high-quality products. After decades of extensive research, Dr. Bengt Ågerup and the company Q-Med in Uppsala, Sweden, succeeded in developing a method to manufacture non-animal, stabilized, hyaluronic acid in the form of a gel, called NASHA. The first application, Restylane, was launched in 1996. To date, more than a million treatments have successfully been carried out with Restylane in more than 60 countries worldwide. What is Restylane?
Restylane is a crystal-clear, biodegradable NASHA (Non-Animal Stabilized Hyaluronic Acid) gel. Hyaluronic acid is a substance that exists naturally in the body. Its most important function is to carry and bind water. Restylane is designed for different purposes and effects, from reducing wrinkles and folds to enhancing facial contours and sculpting lips.
Achieving the look you desire is as easy as it is quick. Unlike some other injectable products for wrinkle treatment and lip enhancement, Restylane is not extracted from animals. No previous skin test is needed, which means that you can have the treatment immediately.
During treatment, Restylane is injected into the skin in tiny amounts with a very fine needle. When injected into the skin, Restylane produces volume that smoothes the wrinkle or fold, shapes the facial contour or enhances the lips in a natural way. The result is immediate. The method of injecting Restylane is fast and safe and leaves no scars or other traces on the face.
How long does Restylane last?
Results are immediate and can last from 6 months or longer; a duration that is two to three times longer than collagen. Unlike permanent treatments or implants, Restylane always offers the chance to re-evaluate the need when the initial effect has subsided. A follow-up treatment can be performed at any time after the previous treatment. Clinical experience indicates that regular follow-up treatments enhance duration.
Possible Side Effects
Immediately after the treatment, you can expect a slight redness, swelling, tenderness and an itching sensation in the treated area. This is a normal result of the injection. The discomfort is only temporary and generally disappears in a few days. After the 6 to 12 months when Restylane begins to break down, water takes its place. When totally absorbed, Restylane turns into water and carbon dioxide and disappears without leaving any trace in your body.
Clinical Studies
The efficacy and safety of Restylane have been demonstrated in extensive clinical studies. A randomized, 6-month, double-blind, multi-specialty center compared the efficacy and tolerability of Restylane versus collagen for the fold from the nose to the corner of the mouth (nasolabial folds). The study included 138 patients and showed that 70 % of patients treated with Restylane maintained a clinically significant improvement up to 6 months and that Restylane was significantly more effective at 2 months.
Impressions of beauty change with time – as do our faces as we age. With Restylane, you can have a natural beauty lift with the body’s own material.
Perlane® is approved! Available in our office now!
The Food and Drug Administration (FDA) has approved the long awaited dermal filler, Perlane®, for the treatment of facial folds and wrinkles.; Perlane® joins Restylane® as the newest member of the hyaluronic acid fillers manufactured by Medicis Aesthetics Inc.
The difference between Restylane® and Perlane® is that Perlane® has a larger gel particle size than Restylane and is designed to be injected deeper into the layers of the skin, thus filling in moderate to severe wrinkles and folds that Restylane could not. Perlane will also be a great product to plump lips and shape facial contours by adding volume.

